45 degrees back is typically okay. You can use Visualizer/Orientation or Diagnostic Visualizer to observe how the field of view is tilted.
Note that poses like a hand tilting up 45 degrees to the table becomes 90 degrees to the sensor. The more you push it, these poses can become challenging to detect and would work better in V2 than V1.
Some other orientations like on the side or top-down with hands on a table are not yet supported.